[The potentials of using artificial pulmonary ventilation for maintaining systemic blood flow]

Hemodynamics was studied experimentally in 36 mongrel dogs during ventricular fibrillation (VF) in conditions of controlled lung ventilation with tidal volumes (TV) 7, 14 and 21 ml/kg and minute ventilation (MV) 140 ml/(min.kg). Cardiac output determined in ascending aorta varied from 4.1 to 7.3 ml/(min.kg) depending on TV and evaluation period with initial values prior to VF 101-110 ml/(min.kg). In 12 experiments using TV of 14 ml/kg acid-base balance and blood gas composition in central and peripheral circulation compartments have been determined. High HbO2 and pO2 levels in peripheral vessels have been noted; HbO2 difference between aortic blood and caudal vein blood was 37% on minute 30 and 28% between aortic and peripheral venous (femoral vein) blood.