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[Malignant lentigo melanoma]

E A Knudsen1, H K Thomsen

  • 1Dermato-venerologisk afdeling og patologisk afdeling, Bispebjerg Hospital, København.

Ugeskrift for Laeger
|July 18, 1994
PubMed
Summary
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Lentigo maligna (LM), a skin lesion, can transform into malignant melanoma (MM) over time. This study highlights two elderly female cases where LM progressed to MM over extended periods, emphasizing the importance of monitoring.

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Malignant melanoma (MM) is a significant skin cancer.
  • MM can develop from pre-existing nevi, normal skin, or lentigo maligna (LM).
  • LM is a specific type of in-situ melanoma often found on sun-damaged skin.

Observation:

  • Two elderly women, aged 75 and 89, were diagnosed with lentigo maligna (LM).
  • These cases represent the progression of LM over extended periods.
  • The clinical course of LM to invasive MM was monitored.

Findings:

  • One case of LM progressed to malignant melanoma (MM) over a ten-year period.
  • Another case of LM transformed into MM over a two-year period.
  • These findings underscore the potential for LM to become invasive MM.

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Implications:

  • Early detection and monitoring of lentigo maligna are crucial.
  • Understanding the progression timeline of LM to MM can inform clinical management.
  • This highlights the importance of vigilance in dermatological surveillance for elderly patients with sun-damaged skin.