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[Vitamins and skin]

J Fuchs1

  • 1Abteilung II, Johann-Wolfgang-Goethe-Universität, Frankfurt.

Therapeutische Umschau. Revue Therapeutique
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Vitamin deficiencies can cause specific or nonspecific skin and mucosal changes, aiding diagnosis. While some vitamin deficiencies have distinct signs, combined deficiencies often present with varied symptoms, requiring clinical assessment.

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Area of Science:

  • Dermatology
  • Nutritional Science
  • Internal Medicine

Context:

  • Mucocutaneous manifestations are key indicators of vitamin deficiency states.
  • Vitamin substitution or therapy can also precipitate dermatological issues.
  • Combined vitamin deficiencies are common, leading to complex clinical presentations.

Purpose:

  • To review the diagnostic significance of mucocutaneous signs in various vitamin deficiencies.
  • To highlight the challenges in diagnosing vitamin deficiencies based solely on laboratory tests.
  • To emphasize the role of clinical observation and therapeutic response in diagnosis.

Summary:

  • Vitamin deficiencies, often stemming from malnutrition, malabsorption, or genetic factors, manifest as mucocutaneous changes.

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  • While pellagra and scurvy show diagnostic skin signs, other deficiencies present with nonspecific or polymorphic eruptions.
  • Alcoholism and gastrointestinal disorders are primary causes in industrialized nations; suspect vitamin deficiency in related patients with specific dermatoses.

    • Impact:

    • Recognizing specific mucocutaneous signs aids in the early diagnosis of vitamin deficiency diseases.
    • Understanding these signs can guide investigations and therapeutic strategies for patients with malnutrition or malabsorption syndromes.
    • This review underscores the importance of clinical assessment, especially when laboratory results may be unreliable.