Related Experiment Videos
Doppler derived aortic valve resistance in aortic stenosis: its hemodynamic validation
P P Ho1, G L Pauls, D F Lamberton
1Department of Cardiology, Loma Linda University, California.
The Journal of Heart Valve Disease
|May 1, 1994
Summary
Aortic valve resistance (AVR) measured by Doppler echocardiography correlates well with catheterization-derived AVR, offering a potentially more accurate, non-invasive assessment of aortic stenosis severity.
Area of Science:
- Cardiovascular Medicine
- Diagnostic Imaging
- Hemodynamics
Background:
- Limitations of Gorlin formula for aortic valve area estimation are recognized.
- Aortic valve resistance (AVR) is proposed as a more accurate index for aortic stenosis severity.
- AVR traditionally requires invasive catheterization for calculation.
Purpose of the Study:
- To evaluate the accuracy of Doppler echocardiography for deriving AVR.
- To compare Doppler-echo AVR with catheterization-derived AVR in patients with aortic stenosis.
Main Methods:
- Thirty-nine patients with aortic stenosis were studied.
- AVR calculated using mean pressure gradient divided by flow per systolic ejection period.
- Cardiac output measured via thermodilution (catheterization) and Doppler-echo (LVOT VTI x CSA).
Main Results:
- Doppler-echo AVR showed significant correlation (r=0.82, p<0.0001) with catheterization AVR.
- A good correlation was also observed between mean pressure gradients from both methods.
- Doppler-echo derived AVR ranged from 38.5 to 738.2 dyne.sec.cm-5.
Conclusions:
- Doppler-echo derived AVR is a reliable non-invasive parameter.
- This method may serve as an additional tool for assessing aortic stenosis severity.
- Findings support the use of Doppler echocardiography as an alternative to invasive methods.