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[White lentiginosis]

E Grosshans1, D Sengel, E Heid

  • 1Clinique Dermatologique, Hôpitaux Universitaires de Strasbourg, France.

Annales De Dermatologie Et De Venereologie
|January 1, 1994
PubMed
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A rare congenital condition, "white lentiginosis," presents unique guttate hypomelanosis. Histological findings differentiate it from other depigmented macules.

Area of Science:

  • Dermatology
  • Histopathology

Background:

  • Congenital guttate hypomelanosis is a rare condition.
  • This entity has not been previously documented in dermatologic literature.

Observation:

  • A 28-year-old female patient presented with numerous guttate lesions.
  • Lesions were pigmented on sun-exposed limbs and depigmented, papulokeratotic on the trunk.
  • Lesions were congenital and stable over a 4-year follow-up.

Findings:

  • Histological examination revealed lentiginous epidermal hyperplasia with elongated rete ridges.
  • Unusual loss of pigmentation was observed without keratinization disturbance.
  • The unique histological features aid in differentiating this condition from other hypopigmented macules.

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Implications:

  • This case describes a novel dermatologic entity, proposed as "white lentiginosis."
  • Distinct histological characteristics differentiate it from macular leukoderma, genodermatoses-associated hypomelanotic macules, and idiopathic guttate hypomelanoses.