Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Linac-accelerator-radiosurgery

V Sturm1, W Schlegel, O Pastyr

  • 1Department of Stereotactic and Functional Neurosurgery, University of Cologne, Federal Republic of Germany.

Acta Neurochirurgica. Supplementum
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Directional DBS leads show large deviations from their intended implantation orientation.

Parkinsonism & related disorders·2019
Same author

Neuronal spiking in the pedunculopontine nucleus in progressive supranuclear palsy and in idiopathic Parkinson's disease.

Journal of neurology·2019
Same author

Adverse events associated with deep brain stimulation in patients with childhood-onset dystonia.

Brain stimulation·2019
Same author

Radiofrequency-thermoablation: General principle, historical overview and modern applications for epilepsy.

Epilepsy research·2018
Same author

Regarding "Determining the Orientation of Directional Deep Brain Stimulation Electrodes Using 3D Rotational Fluoroscopy".

AJNR. American journal of neuroradiology·2017
Same author

Deep Brain Stimulation of the Nucleus Basalis of Meynert in Alzheimer's Dementia: Potential Predictors of Cognitive Change and Results of a Long-Term Follow-Up in Eight Patients.

Brain stimulation·2016
Same journal

[Psychiatry of brain tumors and the cerebral bases of psychical processes].

Acta neurochirurgica. Supplementum·2014
Same journal

[Arteriography in the differential diagnosis of brain tumors].

Acta neurochirurgica. Supplementum·2014
Same journal

The endogenous ouabain-like sodium pump inhibitor in cold injury-induced brain edema.

Acta neurochirurgica. Supplementum·1994
Same journal

Proposed toxic oxidant inhibitors fail to reduce brain edema.

Acta neurochirurgica. Supplementum·1994
Same journal

A novel aspect of thrombin in the tissue reaction following central nervous system injury.

Acta neurochirurgica. Supplementum·1994
Same journal

Causative role of lysosomal enzymes in the pathogenesis of cerebral lesions due to brain edema under chronic hypertension.

Acta neurochirurgica. Supplementum·1994
See all related articles

Linear accelerators (Linac radiosurgery systems) offer viable intracranial radiosurgery options, delivering precise radiation doses comparable to Gamma-Knife and proton therapy. Accurate mechanical alignment and advanced 3D planning are crucial for optimal outcomes.

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Medical Physics

Background:

  • Intracranial radiosurgery demands high precision for tumor treatment.
  • Linear accelerators (Linac) are increasingly explored for these applications.
  • Comparing Linac capabilities with established methods like Gamma-Knife and proton therapy is essential.

Purpose of the Study:

  • To evaluate the capabilities and limitations of Linac radiosurgery systems for intracranial treatments.
  • To assess the dose gradient characteristics achievable with Linac systems.
  • To identify critical technical requirements for effective Linac-based radiosurgery.

Main Methods:

  • Survey of current linear accelerator (Linac) radiosurgery systems.
  • Analysis of dose gradients based on collimator size (5-54 mm diameter).

Related Experiment Videos

  • Evaluation of mechanical accuracy requirements for isocenter stability.

    • Main Results:

    • Linac systems can create spherical fields from 5-54 mm in diameter.
    • Achievable dose gradients range from 10% (large fields) to 20% (small fields) per millimeter.
    • Mechanical inaccuracies must be below 0.8 mm for optimal stability.
    • Advanced 3D treatment planning systems are indispensable.

    Conclusions:

    • Linac radiosurgery presents a comparable alternative to Gamma-Knife and proton irradiation for intracranial procedures.
    • Precise mechanical alignment and sophisticated 3D planning are vital for successful Linac-based radiosurgery.
    • Future developments in Linac technology hold promise for further advancements in the field.