Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genome organization in prokaryotes

A M Campbell1

  • 1Department of Biological Sciences, Stanford University, California 94305.

Current Opinion in Genetics & Development
|December 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Social-pair judgment bias testing in slow-growing broiler chickens raised in low- or high-complexity environments.

Scientific reports·2023
Same author

Impact of environmental complexity and stocking density on affective states of rainbow trout (Oncorhynchus mykiss).

Animal cognition·2022
Same author

Environmental complexity positively impacts affective states of broiler chickens.

Scientific reports·2021
Same author

Cross-reactivity of anti-dsDNA antibodies.

Immunology today·2014
Same author

Multispecific monoclonal antibodies.

Immunology today·2014
Same author

[Not Available].

Immunology today·2014
Same journal

Temporal trajectories underlying adult neuronal diversity.

Current opinion in genetics & development·2026
Same journal

Transcription regulation of cell fate plasticity - from embryonic development to tissue regeneration.

Current opinion in genetics & development·2026
Same journal

Shared molecular and cellular programs during regeneration of glandular epithelia.

Current opinion in genetics & development·2026
Same journal

Lineage tracing in human cortical development.

Current opinion in genetics & development·2026
Same journal

Cis-regulatory strategies in developmental patterning.

Current opinion in genetics & development·2026
Same journal

GABAergic neuron fate specification and lineage allocation: from development to disorder.

Current opinion in genetics & development·2026
See all related articles

Prokaryotic genomes, typically circular DNA, show surprising variations in organization. Gene and sequence locations are often non-random, influenced by historical events and functional optimization.

Area of Science:

  • Microbiology
  • Genomics
  • Molecular Biology

Background:

  • Prokaryotic genomes are typically double-stranded DNA, organized as single circular chromosomes and plasmids.
  • Recent findings reveal significant variations in prokaryotic genome organization.

Purpose of the Study:

  • To investigate the non-random patterns observed in the location and orientation of genes and repeated sequences within prokaryotic genomes.
  • To explore the underlying causes, including historical events and functional selection, of these non-random genome structures.

Main Methods:

  • Analysis of accumulated genomic data from various prokaryotic species.
  • Comparative genomics to identify patterns in gene and sequence arrangement.
  • Bioinformatic approaches to assess randomness versus non-randomness in genomic structures.

Related Experiment Videos

Main Results:

  • Prokaryotic genome organization exhibits notable deviations from simple random models.
  • The placement and orientation of genes, prophages, and transposons are frequently non-random.
  • Evidence suggests both historical contingency and adaptive selection shape these genomic arrangements.

Conclusions:

  • Prokaryotic genome structures are not entirely random, reflecting a complex interplay of evolutionary forces.
  • Understanding these non-random patterns is crucial for comprehending prokaryotic evolution and function.
  • Further research is warranted to fully elucidate the mechanisms driving specific genomic arrangements.