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Screening-detected and symptomatic ductal carcinoma in situ: mammographic features with pathologic correlation
Purpose:
To compare the mammographic and pathologic features of screening-detected and symptomatic ductal carcinoma in situ (DCIS).
Materials And Methods:
The mammographic and pathologic features of 54 screening-detected and 77 symptomatic cases of DCIS were compared. Patients were aged 30-76 years (mean, 58 years).
Results:
Diffuse involvement was seen in 10 patients (13%) with symptoms but in none of the screening-detected group (P < .05). The disease was radiologically more extensive in the symptomatic group. Calcifications in the symptomatic group (n = 48) were less likely to have a ductal distribution than those in the screening-detected group (n = 48) (30 [63%] vs 40 [83%], respectively; P < .05). At histologic examination in some cases, the symptomatic group (n = 76) included eight (11%) patients with cribriform-micropapillary, large-cell tumors (P < .05) and less comedocarcinoma (20 [26%] vs 23 [45%], respectively; P < .05) compared with the screening-detected group (n = 51).
Conclusion:
The results show differences in the radiologic and pathologic features of screening-detected and symptomatic DCIS.