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Communication of the intracranial space with sphenoid bone marrow in mice

Z Srebro1, E Pierścińska, I Płonkowa

  • 1Department of Embryology and Medical Genetics, Collegium Medicum, Jagiellonian University, Kraków, Poland.

Folia Biologica
|January 1, 1993
PubMed

Tritiated thymidine and Ehrlich ascites tumour cells were injected intrathecally in adult Balb/c mice. Thymidine penetrated easily into the sphenoid bone marrow, where it labelled numerous leukocytes. The microvessel wall constituted a partly penetrable barrier against the infiltration of Ehrlich ascites tumour cells from arachnoid space into the bone marrow. A possible physiological role of the drainage of substances from the brain into the bone marrow is discussed.

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