[Microbiologic and immunologic parameters in patients with abscesses of the abdominal cavity]

Dynamic bacteriological examination of abdominal exudate and wound pus after operations on 131 patients with abdominal abscesses of various localization revealed a variety of microorganisms among which 44.2% were staphylococci, 22.9% enterococci, 64.1% Escherichia coli, 34.2% proteus microorganisms, 31.0% Cl. perfringens, and 90% nonclostridial anaerobes; certain varieties (phagotypes, serogroups) prevailed among them which possessed pathogenetic properties to a greater measure than their other varieties. A greater part of the cultures obtained from the foci of affection were in various microbial associations (2-6 types) and were resistant to the widely used antibiotics--penicillin, streptomycin, chlortetracycline, and retained their sensitivity to antibiotics of the neomycin series and to other agents. Specific antibodies to the causative agents and the products of their vital activity accumulated (two-sevenfold) during the disease in most patients, and the intensity of their increase depended on the development of purulent complications and the patient's age. The dynamics of changes of the antibody titer may confirm the etiology of the abscess and be an indirect index of the prognosis of the disease.