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Immunosuppressive drug therapy of systemic lupus erythematosus
1Division of Rheumatology, University of Michigan Medical Center, Ann Arbor.
Rheumatic Diseases Clinics of North America
|February 1, 1994
Abstract:
This article reviews the biologic effects of cyclophosphamide and azathioprine relevant to the treatment of systemic lupus erythematosus (SLE). Other agents used less commonly for SLE, such as methotrexate, chlorambucil, and cyclosporin-A, receive more limited attention. Clinical studies of efficacy and toxicity of these agents in their treatment of SLE are then described in detail.