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Updated: Aug 13, 2026

Primary Culture of Mouse Dopaminergic Neurons
Published on: September 8, 2014
[The electrical excitability of the peripheral motor neuron in parkinsonism]
Abstract:
Chronaximetry and stimulation electromyography were used in examination of 22 and 18 parkinsonian patients, respectively. The maximal amplitude of H-potential, the ration of the amplitude of the reflex to motor response and other parameters evidenced reduced reflex excitability of the motor neurone pool. The intensity of the stimulus sufficient to evoke threshold H-reflex indicated enhanced reflex excitability of the motoneurons which are likely to form passive tremor. As shown by motor response parameters, direct electric excitability of the motor units was high. Following stereotactic treatment, H-reflex and M-response shifted in the direction of increasing motor units excitability. These changes characterize functional rearrangement of the motor analyzer and correspond to a clinical response.
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