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[Bronchial carcinoid tumor with multiple brain metastasis]
S Takano1, M Saitoh, Y Miyasaka
1Department of Neurosurgery, Kitasato Institute, Medical Center Hospital.
No Shinkei Geka. Neurological Surgery
|April 1, 1994
Summary
This case report details a rare bronchial carcinoid tumor with multiple brain metastases. The study highlights unusual intracranial spread and associated hormonal and radiological findings in a 73-year-old woman.
Area of Science:
- Neuro-oncology
- Endocrinology
- Pulmonology
Background:
- Carcinoid tumors are typically low-grade malignancies with a low risk of metastasis.
- Bronchial carcinoid tumors rarely metastasize, especially to the intracranial space.
Observation:
- A 73-year-old woman presented with ataxia and somnolence, indicative of neurological compromise.
- Hormonal assays revealed elevated gastrin, ACTH, serotonin, and urinary 5-HIAA.
- Radiological imaging identified a left lower lobe lung mass and multiple cystic intracranial tumors.
Findings:
- The bronchial carcinoid tumor exhibited rare intracranial metastasis.
- Cerebral tumors showed characteristic enhancement on CT and MRI, with cystic components and niveau formation.
- Elevated hormone levels suggest a functional carcinoid tumor with paraneoplastic effects.
Implications:
- This case underscores the potential for atypical presentations and widespread metastasis of bronchial carcinoid tumors.
- Highlights the importance of comprehensive radiological and hormonal evaluation in diagnosing rare neuroendocrine tumors.
- Emphasizes the need to consider carcinoid tumors in the differential diagnosis of unexplained neurological symptoms and intracranial lesions.