[A factor activating protein synthesis in rat liver microsomes: its induction by a glucocorticoid hormone]

Injection of glucocorticoid hormone to adrenalectomized rats induces in liver microsomes a factor which stimulates polypeptide synthesis in a cell-free system. The factor is extractable from microsomes by 0.5 M KC1 followed by gel filtration, of the extract. Induction of the activator in glucocorticoid-treated rats contribute higher protein-synthesizing ability of the microsomes following hormone administration.