Related Experiment Video
Updated: Aug 14, 2026
08:09
Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils
Published on: November 16, 2015
Formation of the tonsillar corpuscle
1Division of Anatomy and Cell Biology, UMDS, Guy's Hospital, University of London, U.K.
Functional and Developmental Morphology
|January 1, 1993
Summary
Human palatine tonsils contain structures resembling thymic Hassall's corpuscles. These form from degenerating epithelial cells within microcrypts during immune responses, similar to thymus development.
Area of Science:
- Immunology
- Histology
- Human Anatomy
Background:
- The human palatine tonsil contains unique epithelial structures.
- These structures bear resemblance to thymic Hassall's corpuscles.
Purpose of the Study:
- To investigate the origin and nature of tonsillar epithelial structures.
- To compare these structures with thymic Hassall's corpuscles.
Main Methods:
- Histological examination of human palatine tonsil tissue.
- Analysis of epithelial cell morphology and arrangement.
Main Results:
- Identified epithelial structures near tonsillar crypts.
- These structures exhibit features similar to Hassall's corpuscles.
- Proposed formation mechanism involves microcrypt occlusion and epithelial cell degeneration.
Conclusions:
- Tonsillar corpuscles arise from degenerating epithelial cells within occluded microcrypts during antigenic stimulation.
- Structural similarities to Hassall's corpuscles are attributed to shared endodermal origin and lymphoepithelial organ properties.
More Related Videos
Related Concept Videos
01:13The Cochlea
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
01:03Olfactory Receptors: Location and Structure
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
01:20Taste Buds and Receptors
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
01:20Pharynx
The pharynx, a tubular structure framed by skeletal muscle and lined with mucous membrane, extends continuously from the nasal cavities. It is segmented into three major areas: the nasopharynx, oropharynx, and laryngopharynx.
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
01:18Lymphoid Cells and Tissues
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
01:23Chronic Pharyngitis
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...