Polynuclear fertilization in various stimulation protocols in in vitro fertilization

¹Department of Obstetrics and Gynecology, Asahikawa Medical College, Japan.

International Journal of Fertility and Menopausal Studies

|January 1, 1994

Abstract

Objective:

To investigate the effect of some clinical characteristics, especially various ovarian stimulation protocols, on the occurrence of polypronuclear fertilization.

Methods:

One hundred forty-eight consecutive cycles in 121 patients were treated in our IVF program and 735 oocytes were analyzed retrospectively.

Results:

Multipronuclear fertilization occurred in 33 of 530 fertilized oocytes, an incidence of 6.2%. No significant difference in the incidence of polyploidy was observed between the three stimulation protocols (CC/hMG, hMG, GnRHa/hMG). Number of polypronuclear embryos was found to be correlated with the fertilization rate, concentration of sperm inseminated, and maturity of the oocytes.

Conclusions:

The maturity of the oocytes and the sperm fertilizing capacity should be examined to reduce the incidence of polypronuclear fertilization.

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Objective:

Methods:

Results:

Conclusions:

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