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Magnetic resonance imaging (MRI) of calcium alginate gels
K Potter1, T A Carpenter, L D Hall
1Herchel Smith Laboratory for Medicinal Chemistry, University of Cambridge School of Clinical Medicine, UK.
Magnetic Resonance Imaging
|January 1, 1994
Abstract:
The spatial heterogeneity of calcium alginate gels has been visualised by the variation of image intensity across the gel by one-, two-, and three-dimensional MRI. From the linear dependence of (T2)-1 on alginate concentration it is now possible to use MRI to map alginate concentration gradients within calcium alginate gels noninvasively. Since the concentration of alginate determines the pore size of the gel matrix, those alginate concentration maps will be useful in determining the pore size distribution within the gel, which is important in controlled release applications.