[Pseudomembranous colitis in patients with kidney failure]

Two cases of pseudomembranous colitis in patients with renal failure are presented. Both patients were treated with antibiotics. Clinical course, bacteriologic examination of feces, and endoscopy of the colon plays an important role in the diagnosis of this complication. No gut endoscopy was performed in both patients due to severe disease course. Pseudomembranous colitis was diagnosed by clinical symptoms and bacteriologic examination of feces out of which C. difficile was isolated. Teicoplanin-a drug of a known efficiency in the treatment of C. difficile infection-was given and vancomycin was used in the second patient. We would like to stress that renal failure predisposes to the a development of pseudomembranous colitis. An emphasis is also on the dose adjustments of drugs in renal failure.