[Immunological study of the cellular components of Pseudomonas aeruginosa. Report 1]

Water extracts obtained from acetone culture of 5 strains of Ps. aeruginosa isolated from wounds of patients with severe burns were investigated. These extracts contained exotoxin and capsular mucous cell component. By the data of gel-chromatography the extracts proved to be heterogeneous. Their toxic activity was associated chiefly with the high-molecular fraction. The extracts were active in experiments of immunodiffusion and immunoelectrophoresis with homologous and heterologous antisera. Up to 5 components with a different electrophoretic mobility were found in the extracts. There proved to be a correlation between the content in the extract of protein and its toxicity for mice. Differences between the strains of various O-serological groups were detected in experiments of gel-chromatography.