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[Gamma-vinyl-GABA: first experiences in Italy. II]
1Dipartimento di Scienze Neurologiche, Università degli Studi di Roma La Sapienza.
La Clinica Terapeutica
|March 1, 1994
Abstract:
The long term efficacy of GVG was studied in patients with drug resistant CPC and CPC plus secondarily generalized seizures. GVG was started as monotherapy followed by add-on therapy with carbamazepine (CBZ), phenobarbital (PB), valproate (VPA). The results suggest: 1) loss of efficacy of gamma-vinyl-GABA during long-term use, and 2) at present, GVG appears to be an effective safe antiepileptic drug for initial monotherapy.