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[Sperm allergy of the anaphylactic type]
Summary
A rare case of anaphylaxis to seminal fluid in a 26-year-old female is detailed. Skin tests suggest a protein antigen with a molecular weight around 14,100 is responsible for these severe allergic reactions.
Area of Science:
- Allergy and Immunology
- Reproductive Medicine
- Biochemistry
Context:
- Anaphylaxis, a severe allergic reaction, can be triggered by various substances.
- Seminal plasma hypersensitivity is a rare condition causing allergic symptoms after intercourse.
- This case highlights a specific instance of anaphylaxis attributed to seminal fluid.
Purpose:
- To report a case of anaphylaxis to seminal fluid.
- To investigate the nature of the seminal fluid allergen.
- To compare findings with existing literature on similar cases.
Summary:
- A 26-year-old female experienced anaphylactic symptoms including pruritus, mucosal edema, asthma, and shock after exposure to her husband's seminal fluid.
- Skin tests using a chromatographically separated seminal plasma fraction indicated the allergen is protein-based with a molecular weight of approximately 14,100 Daltons.
- These findings align with previous reports suggesting a protein antigen in seminal fluid causes such allergic reactions, with molecular weights ranging from 12,400 to 24,000 Daltons.
Impact:
- Contributes to understanding rare allergic reactions to seminal fluid.
- Provides evidence for the protein nature and molecular weight of the seminal fluid allergen.
- Informs clinical diagnosis and management of patients with suspected seminal plasma hypersensitivity.