[The immunological status of patients with vesicular eruptions on the oral mucosa]

Immunologic examinations of 14 patients with vesicular form of lichen ruber and benign nonacantholytic pemphigus of the buccal mucosa alone, as well as of those with erythema exudativum multiforme demonstrated a normal (and even increased) response of immunity system to a chronic antigenic stimulus. The T system was found not involved, and a reduction of the share of B cells was revealed. The results are indicative of strained functioning of the immunity system paralleled by quantitative exhaustion of the B component.