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[Clinical experience with Arwin (author's transl)]

H Hess, E Keil-Kuri, M Marshall

    MMW, Munchener Medizinische Wochenschrift
    |August 8, 1975
    PubMed
    Summary
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    Arwin effectively treated peripheral arterial blood flow disorders, eliminating pain at rest in over 80% of stage III patients. It also showed promise in combination therapy for complex cases.

    Area of Science:

    • Vascular Surgery
    • Pharmacology

    Background:

    • Peripheral arterial blood flow disorders significantly impact patient quality of life.
    • Current treatments have limitations, especially in advanced disease stages.

    Purpose of the Study:

    • To evaluate the efficacy of Arwin in treating peripheral arterial blood flow disorders.
    • To assess Arwin's role in combination therapy for complex cases.

    Main Methods:

    • Retrospective analysis of 52 patient cases treated with Arwin.
    • Comparison of outcomes in different disease stages (III and IV).
    • Evaluation of Arwin in combination with streptokinase for thrombolysis.

    Main Results:

    • Over 80% of stage III patients achieved pain-free status.

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  • Stage IV treatment success rate was approximately 50%.
  • Combination therapy with Arwin and streptokinase was beneficial in cases with poor outflow.
  • Vascular patency was maintained under Arwin following successful reocclusion lysis.

    • Conclusions:

    • Arwin demonstrates significant efficacy in managing peripheral arterial blood flow disorders, particularly in stage III.
    • Combination therapy involving Arwin offers a valuable alternative for complex arterial conditions.
    • Arwin contributes to maintaining vascular patency post-lysis.