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Lymphoma with bilateral cavernous sinus involvement in early childhood
1Department of Pediatrics, Hacettepe University, School of Medicine, Ankara, Turkey.
Pediatric Neurology
|February 1, 1994
Summary
A rare case of non-Hodgkin lymphoma in a 4-year-old girl presented with complete ophthalmoplegia. Imaging revealed a sinus mass, and biopsy confirmed the diagnosis, marking her as the youngest reported patient with this condition.
Area of Science:
- Pediatric Oncology
- Ophthalmology
- Neuroradiology
Background:
- Malignant lymphoma rarely affects the cavernous sinus, particularly in pediatric patients.
- Cavernous sinus involvement can lead to complex ophthalmological symptoms.
Observation:
- A 4-year-old girl presented with complete ophthalmoplegia and preserved pupillary responses.
- Radiological imaging (CT and MRI) identified a mass infiltrating the cavernous and sphenoid sinuses and posterior ethmoidal cells.
Findings:
- Biopsy confirmed the mass as non-Hodgkin lymphoma.
- This represents the youngest reported case of malignant lymphoma involving the cavernous sinus.
- The patient is the second reported case with bilateral cavernous sinus involvement.
Implications:
- Highlights the importance of considering lymphoma in pediatric patients with unexplained ophthalmoplegia and sinus masses.
- Underscores the need for prompt diagnosis and multidisciplinary management of rare pediatric sinonasal malignancies.
- Contributes to understanding the clinical spectrum and rare presentations of non-Hodgkin lymphoma in children.