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Acquired coagulopathies

J D Kimbrell

    Critical Care Nursing Clinics of North America
    |September 1, 1993
    PubMed
    Summary
    This summary is machine-generated.

    Critical care nurses need to understand acquired coagulopathies, which cause unexpected bleeding in critically ill patients. This review covers coagulation basics, common acquired coagulopathies, and contributing factors like vitamin K deficiency and liver disease.

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    Area of Science:

    • Critical care medicine
    • Hematology
    • Nursing education

    Background:

    • Acquired coagulopathies pose a significant risk of unexpected hemorrhage in critically ill patients.
    • Effective management requires critical care nurses to have a strong understanding of coagulation.
    • Pathophysiology of acquired coagulopathies is complex and multifactorial.

    Purpose of the Study:

    • To review the fundamental process of blood coagulation.
    • To elucidate the pathophysiology of common acquired coagulopathies.
    • To identify factors contributing to the development of acquired coagulopathies in critical care settings.

    Main Methods:

    • Literature review of coagulation physiology.
    • Analysis of conditions leading to acquired coagulopathies.

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  • Identification of iatrogenic and disease-related risk factors.

    • Main Results:

    • Coagulation involves a complex cascade of factors.
    • Acquired coagulopathies can result from vitamin K deficiency, liver disease, and renal disease.
    • Total parenteral nutrition (TPN) and antibiotic use are common contributing factors.

    Conclusions:

    • Nurses require comprehensive knowledge of coagulation and acquired coagulopathies for patient safety.
    • Understanding risk factors is crucial for preventing and managing hemorrhage.
    • This review provides essential information for critical care nursing practice.