[Body fluid and electrolyte content in rat tissues after space flight in the "Space-2044" spacecraft]

Contents of water, sodium, calcium and magnesium in different tissues of the rats stayed in space for 2 weeks in healing period of bone fracture following graded trauma of calf-bones as well as in the rats exposed to a head-down suspension (HDS) have been studied. In microgravity-exposed animals there were no significant changes in fluid-electrolyte composition of the liver, kidney, myocardium, skin, bone (calf bone). Specific "functional load" on the system of fluid-electrolyte homeostasis in the form of operation and subsequent healing of bone fracture did not result in additional changes in fluid and electrolyte contents of body tissues. In the HDS animals there was a significant change in fluid-electrolyte composition of skin, kidney and bone tissue.