[Recurrent nodular panniculitis in alpha 1-antitrypsin deficiency. Successful dapsone therapy]

We present a 59-year-old woman with chronically relapsing and necrotizing nodular panniculitis and associated alpha 1-antitrypsin deficiency. All cutaneous symptoms cleared for the first time in 10 years once she started treatment with dapsone. Chronic panniculitis should lead the clinician to determine plasma alpha 1-antitrypsin levels in more cases.