Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hepatox: database on hepatotoxic drugs]

A Quinton1, P Latry, M Biour

  • 1Service des Maladies de l'Appareil Digestif, Hôpital Saint-André, Bordeaux.

Gastroenterologie Clinique Et Biologique
|January 1, 1993
PubMed
Summary

Hepatox is a database of drugs causing liver damage, updated annually. It allows quick access to information on 866 drugs and their associated liver injuries, aiding clinical decision-making.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early diagnosis of fetal ganglionic eminence cysts: imaging, outcome and genetic associations, revealing role of mitochondrial dysfunction.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2026
Same author

[Hospital medication adherence scale development in cardiovascular disorders].

Annales pharmaceutiques francaises·2020
Same author

[Analysis of the discrimination of the final marks after the first computerized national ranking exam in Medicine in June 2016 in France].

La Revue de medecine interne·2019
Same author

[Educational assessment of the first computerized national ranking exam in France in 2016: Opportunities for improvement].

La Revue de medecine interne·2018
Same author

Self-perceived educational needs of junior assistant professors in Conservative Dentistry and Endodontics in France.

European journal of dental education : official journal of the Association for Dental Education in Europe·2018
Same author

Influence of surgical bleeding on the relationship between admission coagulopathy and risk of massive transfusion: lesson from 704 severe trauma patients.

Vox sanguinis·2016

Area of Science:

  • Pharmacology
  • Hepatology
  • Clinical Informatics

Background:

  • Hepatotoxicity is a significant concern in drug therapy.
  • A comprehensive and accessible resource for hepatotoxic drugs is needed for healthcare professionals.

Purpose of the Study:

  • To introduce Hepatox, a database detailing hepatotoxic drugs.
  • To provide a tool for identifying drugs causing liver injury and their associated mechanisms.

Main Methods:

  • Development of a database using Omnis 7 and Visual Basic.
  • Inclusion of 866 drugs by approved name and 1,300 proprietary names in France.
  • Categorization of drugs into 104 pharmacological classes.

Main Results:

  • Instantaneous access to drug hepatotoxicity information by approved name.
  • Easy retrieval of drug components and their hepatotoxic profiles.
  • Facilitation of lists of drugs causing specific hepatic injuries and drug classes inducing certain liver damage types.

Conclusions:

  • Hepatox serves as a valuable resource for identifying and understanding drug-induced liver injury.
  • The database enhances clinical practice by providing rapid access to critical hepatotoxicity data.

Related Experiment Videos