Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Compliance effects on small diameter polyurethane graft patency

N Uchida1, H Kambic, H Emoto

  • 1Cleveland Clinic Foundation, Department of Biomedical Engineering, Ohio 44195.

Journal of Biomedical Materials Research
|October 1, 1993
PubMed
Summary

Compliance matched polyurethane grafts showed decreased compliance post-implantation, unlike noncompliant grafts. Material degradation may contribute to graft failure, not just compliance mismatch.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Pediatric Ewing sarcoma in the rare sites: a clinicopathological analysis of eight cases].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2026
Same author

[Meta-analysis of influencing factors of pulmonary tuberculosis in occupational pneumoconiosis patients in China].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2026
Same author

Enhanced S-Factor for the ^{14}N(p,γ)^{15}O Reaction and Its Impact on the Solar Composition Problem.

Physical review letters·2025
Same author

[Utilization of pre-exposure prophylaxis service against HIV and related factors in young men who have sex with men in Hangzhou].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2025
Same author

[Analysis of the consultation for services and related factors of post-exposure prophylaxis services among college students who were at high risk for HIV infection in Hangzhou].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2025
Same author

[Survival status and influencing factors of death risk of HIV-infected patients in Hangzhou, 2004-2023].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2024

Area of Science:

  • Biomaterials Science
  • Vascular Surgery
  • Polymer Chemistry

Background:

  • Synthetic vascular grafts aim to replicate natural vessel properties.
  • Compliance mismatch between grafts and native arteries is a known issue.
  • Optimizing graft compliance is crucial for long-term patency and function.

Purpose of the Study:

  • To compare the in vivo performance of compliance-matched and noncompliant polyurethane grafts.
  • To evaluate the impact of compliance on graft patency and anastomotic hyperplasia.
  • To investigate potential causes of graft failure in a canine carotid artery model.

Main Methods:

  • Fabrication of microporous polyurethane grafts with a gelatin coating.
  • In vitro and in vivo compliance measurements using ultrasonic devices.

Related Experiment Videos

  • Assessment of anastomotic hyperplasia and graft patency at autopsy.
  • Analysis of explanted grafts for material degradation using spectroscopy and chromatography.

    • Main Results:

    • Compliance-matched grafts exhibited a significant decrease in compliance after implantation.
    • Noncompliant grafts maintained consistent compliance throughout the study period.
    • Distal anastomotic hyperplasia was significantly greater in compliance-matched grafts.
    • Graft patency rates were 64% for compliant and 50% for noncompliant grafts.
    • Evidence of polyurethane graft material degradation was observed.

    Conclusions:

    • Compliance mismatch alone may not be the sole determinant of graft failure.
    • Material degradation, suture technique, and capsule formation are potential contributing factors.
    • Further research is needed to elucidate the multifactorial nature of synthetic graft failure.