The need for replication
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Updated: Nov 8, 2026

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome
Published on: March 22, 2018
1Department of Speech Pathology and Audiology, University of Alberta, Edmonton, Canada.
Abstract:
Replication provides verification and disconfirmation functions for the scholarly fields. Relatively few replications were found in a survey of studies in JSHD and JSHR over a recent decade. Based on the probabilities of Type I and Type II errors, there are likely to be approximately 50 to 250 false findings in this literature. Because many studies had relatively small sample sizes, replication would be helpful for extending the generalization of their results. These data underscore the urgency for more replications in the field.
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