[Primary non-Hodgkin lymphoma of the prostate: a case report]

A 24-year-old man presented with gross hematuria and pain on micturition. Cystoscopically the prostatic urethra appeared to be pale, edematous and partly elevated mucosa, from which multiple biopsy specimens were taken by TUR-P. A pathological diagnosis of malignant lymphoma (diffuse and large-cell type, according to the LSG classification: B-cell origin according to immunohistochemistry) was established. The results of the physical examination and imaging studies were compatible with the diagnosis of primary lymphoma of the prostate. The patient underwent a combination chemotherapy consisting of vincristine, cyclophosphamide, adriamycin and prednisolone. After completion of 6 courses of chemotherapy over 7 months, another TUR biopsy of the prostate confirmed complete remission. Now, 1 year after completion of chemotherapy, he remains free of the disease. To our knowledge, this is the 21st clinical case of lymphoma of the prostate ever reported in the Japanese literature.