Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone changes in sickle cell anaemia

M F Omojola1, S Annobil, F Adzaku

  • 1Department of Medicine (Radiology), College of Medicine, King Saud University, Abha, Arabia.

East African Medical Journal
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of prehabilitation interventions on pelvic floor muscle outcomes in patients with gynecological cancers: a systematic review.

BMC women's health·2026
Same author

PARADOXICAL ELEVATION OF PLATELET INDICES IN SUDANESE PATIENTS WITH CHRONIC HEPATITIS B: A CROSS-SECTIONAL ANALYSIS.

Georgian medical news·2025
Same author

ASSOCIATION BETWEEN ANTI-THYROID PEROXIDASE ANTIBODY LEVEL AND THYROID FUNCTION PROFILE IN TYPE 2 DIABETIC PATIENTS.

Georgian medical news·2025
Same author

Early Outcome of Closed Lateral Internal Sphincterotomy in the Treatment of Chronic Anal Fissure Compared to Open Method.

Mymensingh medical journal : MMJ·2025
Same author

Evaluation of Serum CA 19-9 as a Diagnostic Marker for Pancreatic Malignancy.

Mymensingh medical journal : MMJ·2024
Same author

Prevalence and risk estimates of Cryptosporidium oocysts infection associated with consumption of raw-eaten vegetables in Maiduguri metropolis LGAs, Northeast Nigeria.

Scientific reports·2023

Sickle cell anaemia (SCA) causes diverse bone changes in Saudi Arabia, including common infarctions and hyperplasia. Spinal issues and early avascular necrosis of the femoral head are notable in SCA patients.

Area of Science:

  • Orthopedics
  • Radiology
  • Hematology

Background:

  • Sickle cell anaemia (SCA) is a genetic blood disorder with known skeletal manifestations.
  • Radiographic evidence of bone changes in SCA patients in Saudi Arabia requires further characterization.

Purpose of the Study:

  • To analyze the spectrum of skeletal system bone changes in sickle cell anaemia patients in the Assir Region of Saudi Arabia.
  • To compare the prevalence and severity of bone changes with existing literature.

Main Methods:

  • Retrospective analysis of radiographs from 50 SCA patients.
  • Radiographs were taken over a three-year period.
  • Assessment of various bone structures for changes like infarctions, hyperplasia, and necrosis.

Related Experiment Videos

Main Results:

  • A wide spectrum of bone changes was observed, with infarctions and medullary hyperplasia being common.
  • Spinal changes (osteoporosis, vertebral end plate depression) were more prevalent in younger patients.
  • Avascular necrosis of the femoral head occurred commonly and earlier than previously reported; humeral and radial head necrosis were also noted.

Conclusions:

  • Bone changes in sickle cell anaemia patients in Saudi Arabia are common and potentially more severe than in other populations.
  • Early onset of avascular necrosis of the femoral head is a significant finding.
  • While common bone changes are prevalent, complications like osteomyelitis and fractures were infrequent.