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Related Experiment Videos

The "88% saturation test": a simple lung function test for young children

C L Wagner1, J G Brooks, S E Richter

  • 1Department of Pediatrics, Children's Hospital, Medical University of South Carolina, Charleston 29425.

Pediatrics
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

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The 88% saturation test (88%-SAT) shows promise for identifying reactive airways disease in young children who cannot perform standard spirometry. This test demonstrated higher sensitivity and specificity than spirometry in detecting this condition.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Diagnostic Testing

Background:

  • Standard spirometry is challenging for young children unable to perform forced expiratory maneuvers.
  • The 88% saturation test (88%-SAT) was developed as an alternative for assessing respiratory function.
  • Previous adult studies indicated 88%-SAT's potential in identifying asthma-related desaturation.

Purpose of the Study:

  • To evaluate the efficacy of the 88%-SAT in identifying reactive airways disease in young children.
  • To compare the performance of 88%-SAT with standard spirometry in this pediatric population.

Main Methods:

  • The study enrolled 33 former premature infants (5-7 years old) at a tertiary care hospital.
  • The 88%-SAT involved breathing a 12% oxygen/nitrogen mixture until oxygen saturation (SaO2) dropped to 88% or for 10 minutes.

Related Experiment Videos

  • Results were compared with standard spirometry and parental questionnaires.

    • Main Results:

    • The 88%-SAT identified reactive airways disease in all 7 children with a history of the condition, showing 100% sensitivity and 87% specificity.
    • Spirometry had lower sensitivity (75%) and specificity (63%) for reactive airways disease.
    • Children unable to complete spirometry often could complete the 88%-SAT, suggesting its utility in uncooperative or developmentally delayed children.

    Conclusions:

    • The 88%-SAT appears more effective than spirometry for diagnosing reactive airways disease in young, uncooperative, or developmentally delayed children.
    • The hypoxic gas mixture in the 88%-SAT may act as an airway challenge, revealing decreased oxygenation in those with reactive airways.