[Stomach neoplasm in patients with gastric ulcer]

The authors analysed the course of the disease in 903 patients with gastric ulcer and in 406 cases of gastric carcinoma which developed in patients suffering from peptic ulcer. Among 345 patients who did not undergo operation, in 24 (7%) carcinoma occurred in the edge of the ulcer or in the cicatrix. Initial stages (I-II) were revealed in 19 patients. Dysplasia of the mucous membrane was found in most patients 1-9 years before the occurrence of carcinoma. Patients with gastric ulcer belong to the risk group. The risk is highest in II and III degree dysplasia and atrophic gastritis. In III degree dysplasia surgical treatment must be considered.