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Nalmefene in the treatment of interstitial cystitis
1Department of Urology, Mt. Sinai School of Medicine, New York, New York.
The Urologic Clinics of North America
|February 1, 1994
Abstract:
Nalmefene is a new narcotic antagonist that is structurally similar to naloxone and naltrexone. The drug is a long-acting oral agent that is a pure opiate antagonist without agonist activity. Nalmefene appears to be a safe and effective compound for the treatment of interstitial cystitis. Longer-term studies and Phase III randomized trials need to be completed to substantiate these encouraging findings.