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[Methotrexate-citrovorum factor individualized reduced dose therapy for ectopic pregnancy: report of 20 cases]
1Capital Medical College, Xuanwu Hospital.
Abstract:
In twenty patients with ectopic pregnancy who received treatment using methotrexate-citrovorum factor in an individualized reduced dose regimen 17 cases were successfully treated, 4 required one course of therapy, 8 required two courses, 4 required three courses, only 1 required four courses, according to the difference in the speed of hCG reduction. The success rate was 85.0%, two cases got intrauterine pregnancy within 6 months after the treatment. Three ruptured cases during treatment were operated upon. The pathologic findings at the ectopic site were chorionic bleeding, necroses, with dissolution of trophoblastic cells.
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