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Correction of thrombocytopenia with dapsone in the primary antiphospholipid syndrome

J M Durand1, P Lefevre, G Kaplanski

  • 1Department of Internal Medicine, CHU Sainte Marguerite, Marseille, France.

A 25-year-old woman with the antiphospholipid syndrome developed severe thrombocytopenia (18 x 10(9)/l), which was promptly corrected by treatment with dapsone. The mechanisms for the apparent therapeutic effect of dapsone are discussed.

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