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Spice allergy evaluated by results of patch tests
1Department of Dermatology, Ochsner Clinic, New Orleans, Louisiana 70121.
Cutis
|November 1, 1993
Summary
Spice allergies can cause contact dermatitis, but specific tests are lacking. This study identified ginger, nutmeg, and oregano as common spice allergens in patients with suspected skin reactions.
Area of Science:
- Dermatology
- Allergology
- Toxicology
Background:
- Allergic contact dermatitis (ACD) from spices is a recognized condition.
- Standardized commercial patch tests for spice allergens are not readily available.
- Diagnosis often relies on clinical suspicion and non-standardized testing methods.
Observation:
- Fifty-five patients with suspected contact dermatitis underwent patch testing with various spices at 10% and 25% concentrations in petrolatum.
- Positive patch test reactions were most frequently observed with ginger, nutmeg, and oregano.
- Reactions at a single concentration, particularly 25%, were noted for several spices, possibly indicating allergic thresholds or irritant reactions.
Findings:
- Ginger, nutmeg, and oregano were identified as the most common spice allergens among the tested patients.
- Higher concentrations (25%) were more likely to elicit a positive reaction in patients sensitive to a single concentration.
- Three patients demonstrated patch test results considered clinically relevant for spice allergy.
Implications:
- This research highlights key spice allergens relevant to contact dermatitis diagnosis.
- The findings may inform the development of more specific diagnostic tools for spice-induced allergic reactions.
- Understanding concentration-dependent reactions can aid in differentiating true allergy from irritant responses.