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Bacteriology of bile in obstructive jaundice
G R Kumari1, V K Beena, R Ramani
1Department of Microbiology, Kasturba Medical College, Manipal.
Indian Journal of Pathology & Microbiology
|July 1, 1993
Summary
Bile cultures from obstructive jaundice patients frequently showed bacterial growth, with Escherichia coli being the most common aerobe. Most isolated aerobic bacteria were sensitive to gentamycin.
Area of Science:
- Microbiology
- Hepatobiliary Medicine
- Infectious Diseases
Background:
- Obstructive jaundice can lead to biliary tract infections.
- Understanding the microbial profile of biliary infections is crucial for effective treatment.
Purpose of the Study:
- To identify aerobic and anaerobic organisms in bile from patients with obstructive jaundice.
- To determine the antibiotic sensitivity of isolated bacteria, particularly to gentamycin.
Main Methods:
- Bile samples were collected from 25 patients diagnosed with obstructive jaundice.
- Samples underwent aerobic and anaerobic bacterial culturing.
- Isolated organisms were identified, and their sensitivity to antibiotics was tested.
Main Results:
- Twenty-one out of 25 bile samples (84%) yielded positive bacterial cultures.
- Mixed bacterial growth was observed in 5 samples (20%).
- Escherichia coli was the most frequently isolated aerobic organism, and Bacteroides fragilis was the sole anaerobic isolate. The majority of aerobic isolates demonstrated sensitivity to gentamycin.
Conclusions:
- Bacterial infection is common in obstructive jaundice.
- Escherichia coli is a prevalent pathogen in this condition.
- Gentamycin shows good efficacy against common aerobic bacteria found in obstructive jaundice.