Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thinking about genetic redundancy

J H Thomas1

  • 1Department of Genetics, University of Washington, Seattle 98195.

Trends in Genetics : TIG
|November 1, 1993
PubMed
Summary
This summary is machine-generated.

Genetic redundancy, where multiple genes perform similar functions, is common but evolutionarily puzzling. This study explores four mechanisms by which natural selection may actively maintain this genetic redundancy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Observation of Charmonium Sequential Suppression in Heavy-Ion Collisions at the Relativistic Heavy Ion Collider.

Physical review letters·2026
Same author

Energy Independence of the Collins Asymmetry in p^{↑}p Collisions.

Physical review letters·2026
Same author

Precision Measurement of Net-Proton-Number Fluctuations in Au+Au Collisions at RHIC.

Physical review letters·2025
Same author

Measurement of Two-Point Energy Correlators within Jets in p+p Collisions at sqrt[s]=200  GeV.

Physical review letters·2025
Same author

Onset of Constituent Quark Number Scaling in Heavy-Ion Collisions at RHIC.

Physical review letters·2025
Same author

Measurement of In-Medium Jet Modification Using Direct Photon+Jet and π^{0}+Jet Correlations in p+p and Central Au+Au Collisions at sqrt[s_{NN}]=200  GeV.

Physical review letters·2025
Same journal

The future of marsupial gene editing: What's in the (tool) pouch?

Trends in genetics : TIG·2026
Same journal

Genetic suppressors as new therapeutic targets for Mendelian diseases.

Trends in genetics : TIG·2026
Same journal

Beyond housekeeping: snRNA diversity, regulation, and human disease.

Trends in genetics : TIG·2026
Same journal

Rethinking mitochondrial metabolism: Intraindividual variability meets population constraints.

Trends in genetics : TIG·2026
Same journal

A role for epigenetics in rapid adaptation.

Trends in genetics : TIG·2026
Same journal

The myth of asexual fungi.

Trends in genetics : TIG·2026
See all related articles

Area of Science:

  • Evolutionary biology
  • Genetics

Background:

  • Partial functional redundancy among genes is a common observation across diverse organisms.
  • The evolutionary stability of fully redundant functions is questionable without selective pressure.

Purpose of the Study:

  • To investigate the selective value and maintenance mechanisms of genetic redundancy.
  • To explore how natural selection can counteract the loss of redundant gene functions through mutation and drift.

Main Methods:

  • Theoretical discussion of evolutionary mechanisms.
  • Analysis of selective pressures acting on gene function.

Main Results:

  • Identified four distinct mechanisms through which selection can maintain genetic redundancy.

Related Experiment Videos

  • Highlighted the potential evolutionary instability of non-selected redundant functions.

    • Conclusions:

    • Natural selection plays a crucial role in preserving genetic redundancy.
    • Understanding these mechanisms provides insight into genome evolution and stability.