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Nutritional status and immune responses

R K Chandra1, P Sarchielli

  • 1Department of Pediatrics, Memorial University of Newfoundland, St. John's, Canada.

Clinics in Laboratory Medicine
|June 1, 1993
PubMed
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Optimal immune system function relies on good nutrition. Immune function tests can indicate nutritional deficiencies, but protein, ascorbic acid, and zinc are key nutrients for hospitalized patients.

Area of Science:

  • Immunology
  • Nutritional Science
  • Clinical Medicine

Background:

  • The immune system requires adequate nutrition for optimal function.
  • Immune function can serve as an indicator of nutritional status.
  • Specific immune markers like lymphocyte count and skin reactivity are used to assess nutritional deficiency.

Purpose of the Study:

  • To highlight the relationship between nutritional status and immune function.
  • To identify key nutrients crucial for maintaining immune function, particularly in hospitalized patients.
  • To discuss the limitations of using immune function tests for monitoring nutritional therapy.

Main Methods:

  • Review of existing literature on nutrition and immune function.
  • Analysis of common indicators of nutritional deficiency related to immune response.

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  • Identification of critical nutrients often lacking in hospitalized individuals.

    • Main Results:

    • Immune function is directly correlated with nutritional status.
    • Lymphocyte count and skin reactivity are common but limited measures of nutritional deficiency.
    • Protein, ascorbic acid, and zinc are vital nutrients for immune health and frequently deficient in hospitalized patients.

    Conclusions:

    • Maintaining adequate nutritional status is essential for a robust immune system.
    • While immune markers can indicate deficiency, they are not ideal for therapy monitoring.
    • Targeted nutritional support focusing on protein, ascorbic acid, and zinc is crucial for hospitalized patients to support immune function.