Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Atopic diseases and mediators

J Ring1

  • 1University Hospital of Dermatology, Hamburg, Germany.

International Archives of Allergy and Immunology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Atopic diseases involve hypersensitivity to environmental triggers. Histamine release, influenced by various factors, plays a key role, but multiple mediators contribute to these complex conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Properly classifying skin changes. Exanthema--what is what?].

MMW Fortschritte der Medizin·2001
Same author

[Symptomatic therapy of exanthema. Finding the proper externum].

MMW Fortschritte der Medizin·2001
Same author

Once-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study.

International journal of dermatology·2001
Same author

Calcitriol 3 microg g-1 ointment in combination with ultraviolet B phototherapy for the treatment of plaque psoriasis: results of a comparative study.

The British journal of dermatology·2001
Same author

Desloratadine in the treatment of chronic idiopathic urticaria.

Allergy·2001
Same author

[Toxic epidermal necrolysis (drug-induced Lyell's syndrome). I. Clinical features and differential diagnosis].

Deutsche medizinische Wochenschrift (1946)·2001
Same journal

Differences in Reported Anaphylaxis Associated With Common Nonsteroidal Anti-inflammatory Drugs: A Pharmacovigilance Study.

International archives of allergy and immunology·2026
Same journal

Association of Serum Galectin-3 Binding Protein with Acute Exacerbation, Inflammation, and Airway Remodeling in Pediatric Asthma.

International archives of allergy and immunology·2026
Same journal

Effectiveness of a Provincial Law to Improve Epinephrine Use for Anaphylaxis in Schools in Alberta, Canada: A Pre-Post Study.

International archives of allergy and immunology·2026
Same journal

Rab27 a regulates dendritic cell immune tolerogenic capacity.

International archives of allergy and immunology·2026
Same journal

Burden of Hereditary Angioedema in Adults: Impact of Disease and Patient Characteristics.

International archives of allergy and immunology·2026
Same journal

Predictors of Treatment Response to Omalizumab in Children with Chronic Spontaneous Urticaria: A Real World Study.

International archives of allergy and immunology·2026
See all related articles

Area of Science:

  • Immunology
  • Allergy Research

Background:

  • Atopic diseases stem from hypersensitivity to environmental antigens.
  • Clinical symptoms arise from complex interactions of cells and mediators.
  • Increased histamine release is observed in patients with atopic diseases.

Purpose of the Study:

  • To explore the multifaceted nature of atopic diseases.
  • To identify key mediators involved in histamine release.
  • To understand the variability in histamine release and sensitivity.

Main Methods:

  • Review of factors regulating histamine release, including specific mediators and systems.
  • Analysis of individual variations in histamine release and sensitivity.
  • Consideration of circadian variations in histamine levels.

Related Experiment Videos

Main Results:

  • Histamine release is regulated by numerous factors like cytokines, arachidonic acid metabolites, and psychological influences.
  • Individual differences in histamine release and sensitivity are significant.
  • Circadian rhythms affect histamine levels.

Conclusions:

  • Atopic diseases are not attributable to a single mediator but involve a complex interplay of various substances.
  • Specific antagonists can be utilized to investigate the roles of different mediators in atopic conditions.