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A defect in the neuroendocrine axis in rheumatoid arthritis: pathogenetic implications
1United Medical School, Guy's Hospital, London, U.K.
Clinical and Experimental Rheumatology
|March 1, 1993
Abstract:
Evidence is presented that there is a defect in the hypothalamic response to inflammatory stimuli in patients with rheumatoid arthritis which leads to a subnormal cortisol response. This defect may be one factor contributing to the chronicity of RA.