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Isradipine ingestion in a two-year-old child
1Delaware Valley Regional Poison Control Center, One Childrens Center, Philadelphia, PA 19104-4303.
Veterinary and Human Toxicology
|June 1, 1993
Summary
This case study details the first reported overdose of isradipine in a 2-year-old child. The child experienced a temporary drop in blood pressure but recovered fully without lasting effects.
Area of Science:
- Cardiology
- Pediatric Toxicology
- Pharmacology
Background:
- Isradipine is a calcium channel blocker used to treat hypertension.
- Overdoses are rare, especially in pediatric populations.
- Understanding overdose effects is crucial for emergency management.
Observation:
- A 2-year-old male ingested 2.5 mg of isradipine.
- The child presented with a transient drop in arterial pressure.
- No other adverse symptoms were observed.
Findings:
- The pediatric overdose of isradipine was successfully managed with fluid resuscitation.
- The patient demonstrated a rapid recovery without any long-term sequelae.
- This case highlights the potential for hypotension in isradipine overdose.
Implications:
- This report provides valuable data on the clinical presentation and management of pediatric isradipine overdose.
- It underscores the importance of prompt recognition and supportive care in calcium channel blocker toxicity.
- Further research into pediatric calcium channel blocker overdose is warranted.