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Strangles
1Department of Veterinary Science, University of Kentucky, Lexington.
The Veterinary Clinics of North America. Equine Practice
|August 1, 1993
Abstract:
The etiology, epizootiology, pathogenesis, and clinical presentation of strangles are described. Streptococcus equi, the causative organism, is highly host-adapted to Equidae and shows no antigenic variation. Protective immunity apparently is mediated by a combination of serum opsonic and nasopharyngeal mucosal humoral responses. Vaccines based on M protein or inactivated bacterial suspensions may reduce the clinical attack rate by 50%, a level of protection much lower than that produced during recovery from strangles.