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1H editing of 2-deuterated exogenous and natural endogenous D-glucose in biological samples
M Biesemans1, F Kayser, M Van Cauteren
1VUB, High Resolution NMR Centre, Belgium.
Magnetic Resonance in Medicine
|July 1, 1993
Abstract:
A spin-echo based 1H homonuclear pulse sequence, enabling the selective editing of homonuclear first-order J-multiplet types, is presented and analyzed. Its effectiveness in quantification applications is assessed. Its potential usefulness in the quantitative distinction between 2-deuterated and natural D-glucose in biological samples is briefly discussed, with emphasis on studies of hexose metabolism conducted in vitro.