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Metastatic carcinoma to the mandible. Report of two cases

M K O Carroll1, S O Krolls, N G Mosca

  • 1School of Dentistry, University of Mississippi Medical Center.

Oral Surgery, Oral Medicine, and Oral Pathology
|September 1, 1993
PubMed

Abstract:

Two cases of rare metastases from malignant neoplasms to the posterior mandible in young adults are reported. Multiple imaging modalities were necessary to identify the many metastases and, in one case, the suspected primary site. Many of the radiographic images are presented for that case.

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Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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