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Amplitude of M responses. Side to side comparability
S C Colachis1, J P Klejka, D Y Shamir
1Department of Physical Medicine and Rehabilitation, Ohio State University College of Medicine, Columbus 43210.
American Journal of Physical Medicine & Rehabilitation
|February 1, 1993
Summary
This study establishes normal M response amplitudes for the extensor digitorum longus muscle (EDL) using peroneal nerve stimulation. These findings provide crucial reference data for diagnosing early nerve root injuries and predicting recovery.
Area of Science:
- Neuroscience
- Clinical Electrophysiology
Background:
- Accurate assessment of nerve function is crucial for diagnosing neurological disorders.
- Establishing normative data for muscle response amplitudes aids in identifying abnormalities.
Purpose of the Study:
- To determine reference values for the peak amplitude of the M response from the extensor digitorum longus (EDL) muscle.
- To assess the side-to-side variability in EDL M response amplitudes in healthy individuals.
- To provide data for evaluating early focal nerve root injury and prognosis.
Main Methods:
- Conventional peroneal nerve stimulation at the fibular head was used.
- Peak M response amplitude was measured in the EDL muscle of 26 healthy subjects.
- Amplitude measurements were taken for both right and left lower limbs.
Main Results:
- The mean EDL M response amplitude was 6.5 mV (+/- 1.3 mV) for the right and 6.1 mV (+/- 1.2 mV) for the left.
- The mean side-to-side difference in amplitude was 0.4 mV (+/- 1.1 mV).
- Most subjects (25/26) showed side-to-side differences within two standard deviations.
Conclusions:
- The described technique accurately assesses EDL M response amplitude.
- These reference data are valuable for the early detection of nerve root injuries.
- The findings support prognosis evaluation for nerve injury recovery.