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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

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Related Experiment Video

Updated: Jul 25, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

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Published on: December 8, 2014

Case study: gluteal abscess due to Crohn's disease

D A Mayer, R G Zingale, M J Tsapogas

    Ostomy/Wound Management
    |June 1, 1993
    PubMed
    Summary

    Spontaneous retroperitoneal abscesses from Crohn's disease can extend beyond typical pelvic locations, potentially causing gluteal abscesses. This case highlights the importance of considering unusual abscess pathways in Crohn's disease management.

    Area of Science:

    • Gastroenterology
    • Surgical Pathology
    • Infectious Disease

    Background:

    • Crohn's disease (CD) is a chronic inflammatory condition that can lead to intra-abdominal and pelvic abscesses.
    • Retroperitoneal abscesses in CD typically involve the psoas or iliac spaces.
    • Abscesses can spread through fascial planes, leading to unusual locations.

    Observation:

    • A 40-year-old female presented with toxemia and a gluteal abscess, an atypical presentation for Crohn's disease.
    • The abscess tracked from the retroperitoneum, breaching the obturator fascia and sciatic foramen.
    • Initial surgical drainage led to an enterocutaneous fistula.

    Findings:

    • A small bowel barium series confirmed the abscess communicated with the cecum.
    • Pathology revealed Crohn's disease affecting the terminal ileum and right colon.

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  • The patient underwent ileocolectomy for definitive management.

    • Implications:

    • This case underscores that retroperitoneal abscesses in Crohn's disease can present in extrathoracic locations, such as the buttock.
    • Recognizing these unusual pathways is crucial for accurate diagnosis and effective treatment of Crohn's disease complications.
    • Prompt surgical intervention and appropriate medical management are essential for controlling sepsis and managing fistulas.