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Intramuscular prostaglandin (15S)-15-methyl PGF2alpha (THAM) in midtrimester abortion
Prostaglandins
|January 1, 1977
Summary
Intramuscular prostaglandin (15S)-15-Methyl PGF2alpha (THAM) effectively terminated second-trimester pregnancies in most patients. This method showed a high success rate, warranting further clinical investigation for pregnancy termination.
Area of Science:
- Reproductive Medicine
- Pharmacology
Background:
- Second-trimester pregnancy termination presents clinical challenges.
- Prostaglandins are utilized for medical induction of labor and abortion.
Purpose of the Study:
- To evaluate the efficacy and safety of intramuscular prostaglandin (15S)-15-Methyl PGF2alpha (THAM) for second-trimester pregnancy termination.
Main Methods:
- A study involving 63 patients undergoing elective termination of second-trimester pregnancies.
- Administration of intramuscular prostaglandin (15S)-15-Methyl PGF2alpha (THAM).
Main Results:
- An overall success rate of 96.8% was achieved.
- In 44 of 61 successful cases, pregnancy duration ranged from 13 to 17 weeks from the last normal menstrual period.
Conclusions:
- Intramuscular prostaglandin (15S)-15-Methyl PGF2alpha (THAM) is an effective agent for second-trimester pregnancy termination.
- The reported method demonstrates significant success and warrants further clinical evaluation.